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Nebroget ( Vitamin B1 (Thiamine HCl) 100 mg + Vitamin B6(Pyridoxine HCl) 100 mg + Vitamin B12 (Cyanocobalamin) 1000 mcg )

  • Effective Material
    Vitamin B1 (Thiamine HCl) 100 mg + Vitamin B6(Pyridoxine HCl) 100 mg + Vitamin B12 (Cyanocobalamin) 1000 mcg
  • Caliber
    Vitamin B1 (Thiamine HCl) 100 mg + Vitamin B6(Pyridoxine HCl) 100 mg + Vitamin B12 (Cyanocobalamin) 1000 mcg
  • Pharmacologic Form
    - vitaminas
  • Therapeutic Categories
    Vitamins & Minerals
  • Pharmaceutical Form
    F.C. Tablets
Each Nebroget F.C tablet contains:
Vitamin B1 (Thiamine hydrochloride) 100 mg.
Vitamin B6 (Pyridoxine hydrochloride ) 100 mg.
Vitamin B12 (Cyanocobalamin ) 1000 mcg.
Nebroget is essential in certain human metabolism and neuropathic treatments by combination of three vitamins B1, B6, B12 where:
Vitamin B1: is essential coenzyme for carbohydrate metabolism.
Deficiency leads to mental and corporal capacity weakness, digestive system disorders and weight decreasing.
Severe deficiency leads to Beriberi disease, characterized by peripheral neuritis, bradycardia, muscle weakness, and paralysis.
Vitamin B6: is involved in amino acid, carbohydrate and fat metabolism.
Deficiency in adult leads to peripheral neuritis. Deficiency in children also affects the C.N.S.
Vitamin B12: acts as coenzymes in nucleic acid synthesis and also closely involved with folic acid in several important metabolic pathways. Deficiency leads to megaloblastic anemia and neurological damage.
It has analgesic action, and the NEBROGET spectrum is improved due to strengthening action of high doses of vitamin B12 combined with B1 and B6.
Therapeutic indications
Nebroget is indicated for the treatment of:
•    Rheumatism and chronic and acute neuritis. 
•    Diseases accompanied by functional metabolic disturbances due to deficiency of these vitamins.
•    Beriberi disease.
•    Megaloblastic anemia.
Nebroget is also indicated for treatment of:
•    Diabetic polyneuritis.
•    Peripheral and encephalopathic alcoholic polyneuritis.
•    Neuropathies due to other administration drugs.
•    Carditis due to B1 deficiency.
•    Neuropathies due to influenza.
•    Sciatica, lumbago and facial paresis.
Side effect
There have been very rare reports of hypersensitivity reactions (e g. skin rashes, reddening, and vesicle formation) after administration of vitamin B1, but also of vitamin B12, Please consult your doctor or pharmacist if you are concerned about this or any other side effect or if you experience other complaints.
Nebroget coated tablets must not be taken in known hypersensitivity to any of the drug ingredients.
Pregnancy and lactation
•    No adverse effects during pregnancy have been reported after intake of vitamins B1, B6, B12 in the recommended dosage.
•    No studies are available on possible accumulation of vitamins in breast milk beyond the normal range.
•    In the individual case the doctor decides whether Nebroget should be taken during pregnancy or the nursing period.
•    Follow the doctor’s prescription, the method of use and the instruction of the pharmacist.
•    The doctor and pharmacist are experts in medicine, its benefits and risks.
Drug interactions
If taken simultaneously with L-dopa (drug against Parkinson's disease), Nebroget reduces the L-dopa effect.
One F.C Tablet 3 times daily during or after meals, or as prescription of doctor.
Box contains 20 F.C Tablets in blisters with leaflet.
No overdosage symptoms are to be expected in the recommended dosage.
After prolonged intake of considerably higher doses the following complaints may occur:
Vitamin B6: Nerve lesions with sensorimotor disturbances, spasms and, in individual cases, changes in the blood count as well as inflammatory skin reactions after doses of more than 2 g daily (equivalent to 10 Nebroget coated tablets) have been described.
Vitamin B12: Allergic reactions, eczematous skin changes after high doses have been observed in rare cases. If you have forgotten to take tablets, you must not make up for it by doubling the next dose. Simply take the next dose at the usual time
Keep away from children. Store at room temperature below 25 ◦C.